具體其含量的高低可能最為壹種機體內炎癥程度的指標，生物學可以，不知道臨床醫學。
蛋白庫 PDB的解釋
iNOS
Produces nitric oxide (NO) which is a messenger molecule
with diverse functions throughout the body. In macrophages, NO mediates
tumoricidal and bactericidal actions. Also has nitrosylase activity and
mediates cysteine S-nitrosylation of cytoplasmic target proteins such
COX2. Homodimer. Binds SLC9A3R1. By endotoxins and cytokines. Induced by
IFNG/IFN-gamma acting synergistically with bacterial
lipopolysaccharides (LPS), TNF or IL1B/interleukin-1 beta. Expressed in
the liver, retina, bone cells and airway epithelial cells of the lung.
Not expressed in the platelets. Regulated by calcium/calmodulin. Aspirin
inhibits expression and function of this enzyme and effects may be
exerted at the level of translational/post-translational modification
and directly on the catalytic activity. Belongs to the NOS family. 2
isoforms of the human protein are produced by alternative splicing.
Note: This description may include information from UniProtKB.
Protein type: EC 1.14.13.39; Amino Acid Metabolism - arginine and proline; Oxidoreductase
Cellular Component: cortical
cytoskeleton; extracellular space; perinuclear region of cytoplasm;
cytoplasm; peroxisome; vesicle membrane; intracellular; nucleus; cytosol
Molecular Function: protein
homodimerization activity; FAD binding; nitric-oxide synthase activity;
metal ion binding; beta-catenin binding; cAMP-dependent protein kinase
regulator activity; oxidoreductase activity; Hsp90 protein binding;
actin binding; protein kinase binding; calmodulin binding; protein
binding; FMN binding; NADPH-hemoprotein reductase activity; cadherin
binding; iron ion binding; heme binding; nitric-oxide synthase binding;
NADP binding; receptor binding
Biological Process: superoxide
metabolic process; response to lipopolysaccharide; positive regulation
of guanylate cyclase activity; positive regulation of killing of cells
of another organism; positive regulation of vasodilation; ovulation from
ovarian follicle; regulation of cell proliferation; defense response to
bacterium; peptidyl-cysteine S-nitrosylation; response to hypoxia;
arginine catabolic process; negative regulation of blood pressure;
regulation of protein kinase activity; inflammatory response; negative
regulation of protein catabolic process; nitric oxide biosynthetic
process; regulation of insulin secretion; nitric oxide mediated signal
transduction