怎麽啦；妳怎麽了；什麽事
例句
1.What is the matter with you both today?
妳們倆今天怎麽了？
2.What is the matter with you, young man?
年輕人，妳怎麽了？
3.What is the matter with him?
他怎麽了？
4.What is the matter with you? You look pale.
妳怎麼啦？妳看來臉色蒼白。
5.What is the matter with your shirt?
什麽是妳的襯衫呢？